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Viral Hepatitis and Liver Disease

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Clip Scoring System

for Health Care Providers

CLIP Scoring System - Liver Cancer

VariablesScore: 0Score: 1Score: 2

The CLIP score for a patient with hepatocellular carcinoma is calculated by assigning a score (0, 1, or 2) to each of four clinical factors: a) Child-Pugh stage; b) number of tumor nodules and whether the tumor extends through ≤ 50% or > 50% of the liver; c) AFP; and d) portal vein thrombosis.

These scores are added together to yield a CLIP score of 0-6, with median survival by CLIP score as follows:

0 = 42.5 months
1 = 32.0 months
2 = 16.5 months
3 = 4.5 months
4 = 2.5 months
5-6 = 1 month

Child-Pugh stageABC
Tumor morphologyuninodular and extension ≤ 50%multinodular and extension ≤ 50% massive or extension > 50%
AFP (ng/dL)< 400≥ 400
Portal vein thrombosisnoyes