Vaccination is now recommended for all adults age 19 to 59 years and have not previously been vaccinated against hepatitis B virus. In addition, vaccination may be particularly important for those at increased risk for infection with hepatitis B virus including the following:

• Anyone traveling to a region of intermediate to high HBV prevalence (>2%)
• All infants and all unvaccinated children younger than 19 years old
• Persons at risk for HBV infection by sexual exposure
  • Men who have sex with men
  • Persons with multiple sex partners
  • Persons seeking evaluation or treatment for an STD
  • Sex partners of HBSAg+ persons
• Persons at risk for HBV infection by percutaneous or mucosal exposure to blood
  • Anyone who has ever injected drugs
  • Household and needle-sharing contacts of HBsAg-positive persons
  • Residents and staff of facilities for developmentally disabled persons
  • Health care and public safety workers at risk for occupational exposure to blood or blood-contaminated body fluids
  • Persons with end-stage renal disease, including pre-dialysis or any form of dialysis
  • Unvaccinated persons with diabetes who are aged 19 through 59 years (clinician's discretion for unvaccinated adults with diabetes who are 60 or older)
• Others
  • Pregnant women should discuss with their provider
  • Persons with HIV
  • Persons with chronic liver disease including HCV, cirrhosis, fatty liver disease, alcoholic liver disease, and autoimmune hepatitis
  • Inmates of correctional facilities